Publication Highlights
2025
Altab G, Merry BJ, Beckett CW, Raina P, Soriano Arroquia A, Zhang B, Vasilaki A, Goljanek-Whysall K, Pedro de Magalhães J. Unveiling Ageing-Associated and Caloric Restriction-Associated Changes in miRNA Expression in Rat Skeletal Muscle and the Mechanisms Mediating their Effects on Muscle Cell Function. bioRxiv 2024.04.07.588472; doi: https://doi.org/10.1101/2024.04.07.588472
Tischer D, Schranner D, Kallabis S, Braunsperger A, Schönfelder M, Gnad T, Jost PJ, Nesic S, Renziehausen F, Fester L, Buness A, Hasenauer J, Meissner F, Pfeifer A, Wackerhage H, Soriano Arroquia A. miR-196a-5p and miR-342-3p mediate skeletal muscle and thermogenic adipose tissue crosstalk through extracellular vesicles. bioRxiv 2025.05.28.656129; doi: https://doi.org/10.1101/2025.05.28.656129
Telge MG, Evangelakos I, Schlein C. A simple, cost efficient assay for assessing the functional impact of single and multi-gene variant combinations. bioRxiv 2025.07.11.663622; doi: https://doi.org/10.1101/2025.07.11.663622
Scholz JJ, Piel SYL, Evangelakos I, Müller C, Karall D, Reinhart-Steininger B, Steinbrücker K, Stulnig T, Rohde J, Mayr J, Wagner M, Biabani A, Mair T, Müller K, Schlüter H, Weidemann S, Chirico V, Weiler-Normann C, Hagel C, Knisely AS, Heeren J, Schoser B, Kubisch C, Hempel M, Prokisch H, Wortmann SB, Worthmann A, Schlein C. TXNIP is a critical regulator of human cardiometabolic health. medRxiv 2025.06.09.25328488; doi: https://doi.org/10.1101/2025.06.09.25328488
Behrens J, Fuh MM, Haas DT, Jaeckstein MY, Heine M, Siebels B, Worthmann A, Krahmer N, Heeren J, Scheja L. Fructose uptake by brown adipose tissue is independent of carbohydrate response element-binding protein and does not cause elevated de novo lipogenesis. Acta Biochim Biophys Sin (Shanghai). 2025 Dec 18. doi: 10.3724/abbs.2025229. Epub ahead of print. PMID: 41408829.
Mello RM, Gomez Ceballos D, Sandate CR, Wang S, Jouffe C, Agudelo D, Uhlenhaut NH, Thomä NH, Simon MC, Lamia KA. BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma. Nat Commun. 2025 Jul 1;16(1):5834. doi: 10.1038/s41467-025-60904-0. PMID: 40595592; PMCID: PMC12215836.
Llerins Perez M, Gao X, Heimerl L, Wang Y, Schnabl K, Firzlaff U, Luksch H, Klingenspor M, Uhlenhaut NH, Wang D, Li Y. The Hypothalamic–Pituitary–Adrenal Axis Orchestrates Energy Homeostasis during Cold Exposure. bioRxiv 2025.09.18.677113; doi: https://doi.org/10.1101/2025.09.18.677113
Hurkmans KM, Heine M, Rinninger F, Jaeckstein MY, Mineo C, Shaul PW, Heeren J. Endothelial SR-B1 is dispensable for thermogenesis but promotes selective cholesterol uptake in brown adipose tissue. J Lipid Res. 2025 Oct;66(10):100894. doi: 10.1016/j.jlr.2025.100894. Epub 2025 Sep 3. PMID: 40912492; PMCID: PMC12510209.
Behrens J, Wang T, Kilian C, Worthmann A, Herman MA, Heeren J, Adlung L, Scheja L. Single-nucleus mRNA-sequencing reveals dynamics of lipogenic and thermogenic adipocyte populations in murine brown adipose tissue in response to cold exposure. Mol Metab. 2025 Nov;101:102252. doi: 10.1016/j.molmet.2025.102252. Epub 2025 Sep 11. PMID: 40945691; PMCID: PMC12506565.
Kuellmer K, Mönch C, Roch W, Wurmser C, Petersen PSS, Hermannsdóttir H, Hasic M, Emanuelli B, Fromme T. Preadipocyte Uncoupling Protein 1 Expression Invoked by Fibroblast Growth Factors Imprints on Post-Differentiation White and Brown Adipocyte Phenotype. FASEB J. 2025 Oct 31;39(20):e71109. doi: 10.1096/fj.202502663R. PMID: 41099430; PMCID: PMC12529888.
Meyer S, Witt J, Liebold I, López-López T, Ehlen L, Leyk S, Hiefner J, Haas D, Schlein C, Sáez PJ, Krahmer N, Heeren J, Adlung L, Bosurgi L, Worthmann A. Sympathetic signaling directs macrophage efferocytosis in thermogenic adipose tissue. bioRxiv 2025.10.28.685032; doi: https://doi.org/10.1101/2025.10.28.685032
Köker SC, Tsokanos FF, El-Merahbi R, Jha AK, Cicatelli K, Weber P, Mhamane A, Kaltenecker D, Morigny P, Loft A, Klepac K, Maida A, Molocea CE, Hass D, Vogl ES, Alfaro AJ, Sun W, Zitzelsberger H, Unger K, Szendrödi J, Li Y, Diaz MB, Wolfrum C, Bartelt A, Herzig S, Georgiadi A. The TBLR1/TBL1 Co-Factor Complex Acts as a Transcriptional Checkpoint in the Brown Adipose Tissue Response to Prolonged Cold Exposure. FASEB J. 2025 Aug 15;39(15):e70886. doi: 10.1096/fj.202402993RRR. PMID: 40787784; PMCID: PMC12337241.
Braunsperger A, Bauer M, Brahim CB, Seep L, Tischer D, Peitzsch M, Hasenauer J, Figueroa SH, Worthmann A, Heeren J, Dyar KA, Koehler K, Soriano-Arroquia A, Schönfelder M, Wackerhage H. Effects of time-of-day on the noradrenaline, adrenaline, cortisol and blood lipidome response to an ice bath. Sci Rep. 2025 Jan 8;15(1):1263. doi: 10.1038/s41598-025-85304-8. PMID: 39779795; PMCID: PMC11711488.
Hildebrand S, Pfeifer A. The obesity pandemic and its impact on non-communicable disease burden. Pflugers Arch. 2025 May;477(5):657-668. doi: 10.1007/s00424-025-03066-8. Epub 2025 Feb 10. PMID: 39924587; PMCID: PMC12003543.
Seep L, Jost PJ, Lisowski C, Huang H, Grein S, Hermannsdottir H, Kuellmer K, Fromme T, Klingenspor M, Mass E, Kurts C, Hasenauer J. cOmicsArt-a customizable Omics Analysis and reporting tool. Bioinform Adv. 2025 Apr 1;5(1):vbaf067. doi: 10.1093/bioadv/vbaf067. PMID: 40385593; PMCID: PMC12085238.
Huang H, Balzer NR, Seep L, Splichalova I, Blank-Stein N, Viola MF, Franco Taveras E, Acil K, Fink D, Petrovic F, Makdissi N, Bayar S, Mauel K, Radwaniak C, Zurkovic J, Kayvanjoo AH, Wunderling K, Jessen M, Yaghmour MH, Kenner L, Ulas T, Grein S, Schultze JL, Scott CL, Guilliams M, Liu Z, Ginhoux F, Beyer MD, Thiele C, Meissner F, Hasenauer J, Wachten D, Mass E. Kupffer cell programming by maternal obesity triggers fatty liver disease. Nature. 2025 Aug;644(8077):790-798. doi: 10.1038/s41586-025-09190-w. Epub 2025 Jun 18. PMID: 40533564; PMCID: PMC12367551.
Sieckmann K, Winnerling N, Silva Ribeiro DJ, Yüksel S, Kardinal R, Steinheuer LM, Frechen F, Corrêa LH, Schermann G, Klausen C, Blank-Stein N, Schulte-Schrepping J, Osei-Sarpong C, Becker M, Bonaguro L, Beyer M, May-Simera HL, Zurkovic J, Thiele C, Thurley K, Sorokin L, Ruiz de Almodovar C, Mass E, Wachten D. BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue. EMBO J. 2025 Oct;44(19):5315-5336. doi: 10.1038/s44318-025-00524-y. Epub 2025 Aug 20. PMID: 40836034; PMCID: PMC12489102.
Loipfinger S, Grosholz M, Kumar S, Erbilir H, Dyar KA, Müller TD, Grein S, Rozman J, Klingenspor M, Meyer C, Lutter D. Calopy - an advanced framework for the integration and analysis of indirect calorimetry data. Nat Metab. 2025 Jun;7(6):1093-1095. doi: 10.1038/s42255-025-01316-8. PMID: 40562969.
Zhong J, Zareifi D, Weinbrenner S, Hansen M, Klingelhuber F, Nono Nankam PA, Frendo-Cumbo S, Bhalla N, Cordeddu L, de Castro Barbosa T, Arner P, Dahlman I, Muniandy M, Heinonen S, Pietiläinen KH, Hoffmann A, Ghosh A, John D, Tönjes A, Ståhl PL, Böttcher Y, Keller M, Kovacs P, Kerr AG, Langin D, Wolfrum C, Blüher M, Krahmer N, Massier L, Mejhert N, Rydén M. adiposetissue.org: A knowledge portal integrating clinical and experimental data from human adipose tissue. Cell Metab. 2025 Mar 4;37(3):566-569. doi: 10.1016/j.cmet.2025.01.012. Epub 2025 Feb 20. PMID: 39983713.
Nicolaisen TS, Lyster AE, Sjøberg KA, Haas DT, Voldstedlund CT, Lundsgaard AM, Jensen JK, Madsen EM, Nielsen CK, Bloch-Ibenfeldt M, Wewer Albrechtsen NJ, Rose AJ, Krahmer N, Clemmensen C, Richter EA, Fritzen AM, Kiens B. Dietary protein restriction elevates FGF21 levels and energy requirements to maintain body weight in lean men. Nat Metab. 2025 Mar;7(3):602-616. doi: 10.1038/s42255-025-01236-7. Epub 2025 Mar 6. PMID: 40050437; PMCID: PMC11946896.
A Wagner, JH Lautaoja-Kivipelto, K Pehkonen, A Hassinen, M Kuusela, L Röttger, E Herbers, A Ioannidou, S Mädler, I Rothenaigner, S Srinivasan, S Laasonen, MT Rahman, P Elomaa, S Kortetjärvi, A Olsson, O Ukkola, K Hadian, M Mann, H Peltoniemi, KH Pietiläinen, M Klingenspor, KA Virtanen, CE Hagberg, E Pirinen. In vitro model of human subcutaneous adipocyte spheroids for studying mitochondrial dysfunction and mitochondria activating compounds. bioRxiv 2025.04.16.649074; doi: https://doi.org/10.1101/2025.04.16.649074
Pfeifer A, Mikhael M, Niemann B. Inosine: novel activator of brown adipose tissue and energy homeostasis. Trends Cell Biol. 2024 Jan;34(1):72-82. doi: 10.1016/j.tcb.2023.04.007. Epub 2023 May 13. PMID: 37188562.
Haas B, Hass MDS, Voltz A, Vogel M, Walther J, Biswas A, Hass D, Pfeifer A. Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation. Mol Metab. 2024 Jul;85:101956. doi: 10.1016/j.molmet.2024.101956. Epub 2024 May 10. PMID: 38735390; PMCID: PMC11112612.
Brands J, Bravo S, Jürgenliemke L, Grätz L, Schihada H, Frechen F, Alenfelder J, Pfeil C, Ohse PG, Hiratsuka S, Kawakami K, Schmacke LC, Heycke N, Inoue A, König G, Pfeifer A, Wachten D, Schulte G, Steinmetzer T, Watts VJ, Gomeza J, Simon K, Kostenis E. A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors. Nat Commun. 2024 Sep 3;15(1):7684. doi: 10.1038/s41467-024-51991-6. PMID: 39227390; PMCID: PMC11372221.
Niu Z, Hildebrand S, Kappes S, Ali ME, Vogel M, Mikhael M, Ran D, Kozak J, Wiedner M, Richter DF, Lamprecht A, Pfeifer A. Enhanced browning of adipose tissue by mirabegron-microspheres. J Control Release. 2024 Nov;375:601-613. doi: 10.1016/j.jconrel.2024.09.025. Epub 2024 Sep 23. PMID: 39278357.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. NK2R control of energy expenditure and feeding to treat metabolic diseases. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. PMID: 39537932; PMCID: PMC11602716.
Silva Ribeiro DJ, Yüksel S, Dolf A, Wachten D. Isolation and Flow Cytometry Analysis of Macrophages from White Adipose Tissue. Methods Mol Biol. 2024;2713:149-158. doi: 10.1007/978-1-0716-3437-0_10. PMID: 37639121.
Young S, Schiffer C, Wagner A, Patz J, Potapenko A, Herrmann L, Nordhoff V, Pock T, Krallmann C, Stallmeyer B, Röpke A, Kierzek M, Biagioni C, Wang T, Haalck L, Deuster D, Hansen JN, Wachten D, Risse B, Behre HM, Schlatt S, Kliesch S, Tüttelmann F, Brenker C, Strünker T. Human fertilization in vivo and in vitro requires the CatSper channel to initiate sperm hyperactivation. J Clin Invest. 2024 Jan 2;134(1):e173564. doi: 10.1172/JCI173564. PMID: 38165034; PMCID: PMC10760960.
Lerchner J, Hervas LS, Bícego KC, Garcia GS, Oliveira MT, Hasic M, Klingenspor M & Mertens F. A device for rapid calorimetric measurements on small biological tissue samples. J Therm Anal Calorim 149, 8085–8096 (2024). https://doi.org/10.1007/s10973-024-13183-8
Schweiger M, Arredondo-Lasso MN, Friano ME, Gil-Lozano M, Herzig S, Uhlenhaut NH. Lipid sensing nuclear receptors involved in the pathogenesis of fatty liver disease. FEBS Lett. 2024 Dec;598(23):2854-2855. doi: 10.1002/1873-3468.14818. Epub 2024 Feb 13. PMID: 38348593; PMCID: PMC11626999.
Jaeckstein MY, Schulze I, Zajac MW, Heine M, Mann O, Pfeifer A, Heeren J. CD73-dependent generation of extracellular adenosine by vascular endothelial cells modulates de novo lipogenesis in adipose tissue. Front Immunol. 2024 Jan 9;14:1308456. doi: 10.3389/fimmu.2023.1308456. PMID: 38264660; PMCID: PMC10803534.
Behler-Janbeck F, Baranowsky A, Yorgan TA, Jaeckstein MY, Worthmann A, Fuh MM, Gunasekaran K, Tiegs G, Amling M, Schinke T, Heeren J. The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells. Front Endocrinol (Lausanne). 2024 Sep 19;15:1392418. doi: 10.3389/fendo.2024.1392418. Erratum in: Front Endocrinol (Lausanne). 2025 Jan 07;15:1528968. doi: 10.3389/fendo.2024.1528968. PMID: 39363899; PMCID: PMC11446854.
Sass F, Ma T, Ekberg JH, Kirigiti M, Ureña MG, Dollet L, Brown JM, Basse AL, Yacawych WT, Burm HB, Andersen MK, Nielsen TS, Tomlinson AJ, Dmytiyeva O, Christensen DP, Bader L, Vo CT, Wang Y, Rausch DM, Kristensen CK, Gestal-Mato M, In Het Panhuis W, Sjøberg KA, Kernodle S, Petersen JE, Pavlovskyi A, Sandhu M, Moltke I, Jørgensen ME, Albrechtsen A, Grarup N, Babu MM, Rensen PCN, Kooijman S, Seeley RJ, Worthmann A, Heeren J, Pers TH, Hansen T, Gustafsson MBF, Tang-Christensen M, Kilpeläinen TO, Myers MG Jr, Kievit P, Schwartz TW, Hansen JB, Gerhart-Hines Z. NK2R control of energy expenditure and feeding to treat metabolic diseases. Nature. 2024 Nov;635(8040):987-1000. doi: 10.1038/s41586-024-08207-0. Epub 2024 Nov 13. PMID: 39537932; PMCID: PMC11602716.
Schmidt A, Danyel M, Grundmann K, Brunet T, Klinkhammer H, Hsieh TC, Engels H, Peters S, Knaus A, Moosa S, Averdunk L, Boschann F, Sczakiel HL, Schwartzmann S, Mensah MA, Pantel JT, Holtgrewe M, Bösch A, Weiß C, Weinhold N, Suter AA, Stoltenburg C, Neugebauer J, Kallinich T, Kaindl AM, Holzhauer S, Bührer C, Bufler P, Kornak U, Ott CE, Schülke M, Nguyen HHP, Hoffjan S, Grasemann C, Rothoeft T, Brinkmann F, Matar N, Sivalingam S, Perne C, Mangold E, Kreiss M, Cremer K, Betz RC, Mücke M, Grigull L, Klockgether T, Spier I, Heimbach A, Bender T, Brand F, Stieber C, Morawiec AM, Karakostas P, Schäfer VS, Bernsen S, Weydt P, Castro-Gomez S, Aziz A, Grobe-Einsler M, Kimmich O, Kobeleva X, Önder D, Lesmann H, Kumar S, Tacik P, Bhasin MA, Incardona P, Lee-Kirsch MA, Berner R, Schuetz C, Körholz J, Kretschmer T, Di Donato N, Schröck E, Heinen A, Reuner U, Hanßke AM, Kaiser FJ, Manka E, Munteanu M, Kuechler A, Cordula K, Hirtz R, Schlapakow E, Schlein C, Lisfeld J, Kubisch C, Herget T, Hempel M, Weiler-Normann C, Ullrich K, Schramm C, Rudolph C, Rillig F, Groffmann M, Muntau A, Tibelius A, Schwaibold EMC, Schaaf CP, Zawada M, Kaufmann L, Hinderhofer K, Okun PM, Kotzaeridou U, Hoffmann GF, Choukair D, Bettendorf M, Spielmann M, Ripke A, Pauly M, Münchau A, Lohmann K, Hüning I, Hanker B, Bäumer T, Herzog R, Hellenbroich Y, Westphal DS, Strom T, Kovacs R, Riedhammer KM, Mayerhanser K, Graf E, Brugger M, Hoefele J, Oexle K, Mirza-Schreiber N, Berutti R, Schatz U, Krenn M, Makowski C, Weigand H, Schröder S, Rohlfs M, Vill K, Hauck F, Borggraefe I, Müller-Felber W, Kurth I, Elbracht M, Knopp C, Begemann M, Kraft F, Lemke JR, Hentschel J, Platzer K, Strehlow V, Abou Jamra R, Kehrer M, Demidov G, Beck-Wödl S, Graessner H, Sturm M, Zeltner L, Schöls LJ, Magg J, Bevot A, Kehrer C, Kaiser N, Turro E, Horn D, Grüters-Kieslich A, Klein C, Mundlos S, Nöthen M, Riess O, Meitinger T, Krude H, Krawitz PM, Haack T, Ehmke N, Wagner M. Next-generation phenotyping integrated in a national framework for patients with ultrarare disorders improves genetic diagnostics and yields new molecular findings. Nat Genet. 2024 Aug;56(8):1644-1653. doi: 10.1038/s41588-024-01836-1. Epub 2024 Jul 22. Erratum in: Nat Genet. 2025 Jul;57(7):1790-1791. doi: 10.1038/s41588-025-02271-6. PMID: 39039281; PMCID: PMC11319204.
Willim J, Woike D, Greene D, Das S, Pfeifer K, Yuan W, Lindsey A, Itani O, Böhme AL, Tibbe D, Hönck HH, Hassani Nia F; Undiagnosed Diseases Network; Zech M, Brunet T, Faivre L, Sorlin A, Vitobello A, Smol T, Colson C, Baranano K, Schatz K, Bayat A, Schoch K, Spillmann R, Davis EE, Conboy E, Vetrini F, Platzer K, Neuser S, Gburek-Augustat J, Grace AN, Mitchell B, Stegmann A, Sinnema M, Meeks N, Saunders C, Cadieux-Dion M, Hoyer J, Van-Gils J, de Sainte-Agathe JM, Thompson ML, Bebin EM, Weisz-Hubshman M, Tabet AC, Verloes A, Levy J, Latypova X, Harder S, Silverman GA, Pak SC, Schedl T, Freson K, Mumford A, Turro E, Schlein C, Shashi V, Kreienkamp HJ. Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors. Nat Commun. 2024 Sep 10;15(1):7909. doi: 10.1038/s41467-024-52095-x. PMID: 39256359; PMCID: PMC11387733.
Behrens J, Braren I, Jaeckstein MY, Lilie L, Heine M, Sass F, Sommer J, Silbert-Wagner D, Fuh MM, Worthmann A, Straub L, Moustafa T, Heeren J, Scheja L. An efficient AAV vector system of Rec2 serotype for intravenous injection to study metabolism in brown adipocytes in vivo. Mol Metab. 2024 Oct;88:101999. doi: 10.1016/j.molmet.2024.101999. Epub 2024 Jul 31. PMID: 39094948; PMCID: PMC11362766.
Liebold I, Al Jawazneh A, Casar C, Lanzloth C, Leyk S, Hamley M, Wong MN, Kylies D, Gräfe SK, Edenhofer I, Aranda-Pardos I, Kriwet M, Haas H, Krause J, Hadjilaou A, Schromm AB, Richardt U, Eggert P, Tappe D, Weidemann SA, Ghosh S, Krebs CF, A-Gonzalez N, Worthmann A, Lohse AW, Huber S, Rothlin CV, Puelles VG, Jacobs T, Gagliani N, Bosurgi L. Apoptotic cell identity induces distinct functional responses to IL-4 in efferocytic macrophages. Science. 2024 Apr 5;384(6691):eabo7027. doi: 10.1126/science.abo7027. Epub 2024 Apr 5. PMID: 38574142.
Musiol E, Fromme T, Hau J, Di Pizio A, Klingenspor M. Comparative functional analysis reveals differential nucleotide sensitivity between human and mouse UCP1. Acta Physiol (Oxf). 2024 Sep;240(9):e14209. doi: 10.1111/apha.14209. Epub 2024 Jul 29. PMID: 39072954.
Ludzki AC, Hansen M, Zareifi D, Jalkanen J, Huang Z, Omar-Hmeadi M, Renzi G, Klingelhuber F, Boland S, Ambaw YA, Wang N, Damdimopoulos A, Liu J, Jernberg T, Petrus P, Arner P, Krahmer N, Fan R, Treuter E, Gao H, Rydén M, Mejhert N. Transcriptional determinants of lipid mobilization in human adipocytes. Sci Adv. 2024 Jan 5;10(1):eadi2689. doi: 10.1126/sciadv.adi2689. Epub 2024 Jan 3. PMID: 38170777; PMCID: PMC10776019.
Weighardt H, Shapiro M, Mayer M, Förster I, Stockinger B, Diny NL. The AHR repressor limits expression of antimicrobial genes but not AHR-dependent genes in intestinal eosinophils. J Leukoc Biol. 2024 Jul 25;116(2):369-378. doi: 10.1093/jleuko/qiae105. PMID: 38701199; PMCID: PMC11271977.
Hosni S, Kilian V, Klümper N, Gabbia D, Sieckmann K, Corvino D, Winkler A, Saponaro M, Wörsdörfer K, Schmidt D, Hahn O, Zanotto I, Bertlich M, Toma M, Bald T, Eckstein M, Hölzel M, Geyer M, Ritter M, Wachten D, De Martin S, Alajati A. Adipocyte Precursor-Derived NRG1 Promotes Resistance to FGFR Inhibition in Urothelial Carcinoma. Cancer Res. 2024 Mar 4;84(5):725-740. doi: 10.1158/0008-5472.CAN-23-1398. PMID: 38175774; PMCID: PMC10911805.
Brands J, Bravo S, Jürgenliemke L, Grätz L, Schihada H, Frechen F, Alenfelder J, Pfeil C, Ohse PG, Hiratsuka S, Kawakami K, Schmacke LC, Heycke N, Inoue A, König G, Pfeifer A, Wachten D, Schulte G, Steinmetzer T, Watts VJ, Gomeza J, Simon K, Kostenis E. A molecular mechanism to diversify Ca2+ signaling downstream of Gs protein-coupled receptors. Nat Commun. 2024 Sep 3;15(1):7684. doi: 10.1038/s41467-024-51991-6. PMID: 39227390; PMCID: PMC11372221.
Lerchner J, Hervas LS, Bícego KC, Garcia GS, Oliveira MT, Hasic M, Klingenspor M & Mertens F. A device for rapid calorimetric measurements on small biological tissue samples. J Therm Anal Calorim 149, 8085–8096 (2024). https://doi.org/10.1007/s10973-024-13183-8
Seep L, Grein S, Splichalova I, Ran D, Mikhael M, Hildebrand S, Lauterbach M, Hiller K, Ribeiro DJS, Sieckmann K, Kardinal R, Huang H, Yu J, Kallabis S, Behrens J, Till A, Peeva V, Strohmeyer A, Bruder J, Blum T, Soriano-Arroquia A, Tischer D, Kuellmer K, Li Y, Beyer M, Gellner AK, Fromme T, Wackerhage H, Klingenspor M, Fenske WK, Scheja L, Meissner F, Schlitzer A, Mass E, Wachten D, Latz E, Pfeifer A, Hasenauer J. From Planning Stage Towards FAIR Data: A Practical Metadatasheet For Biomedical Scientists. Sci Data. 2024 May 22;11(1):524. doi: 10.1038/s41597-024-03349-2. PMID: 38778016; PMCID: PMC11111677.
Klingelhuber F, Frendo-Cumbo S, Omar-Hmeadi M, Massier L, Kakimoto P, Taylor AJ, Couchet M, Ribicic S, Wabitsch M, Messias AC, Iuso A, Müller TD, Rydén M, Mejhert N, Krahmer N. A spatiotemporal proteomic map of human adipogenesis. Nat Metab. 2024 May;6(5):861-879. doi: 10.1038/s42255-024-01025-8. Epub 2024 Apr 2. PMID: 38565923; PMCID: PMC11132986.
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