CRC/TRR333 - BATenergy
Brown and Beige Fat - Organ Crosstalk, Signaling and Energetics

Welcome to the web page of the CRC/TRR333

The Collaborative Research Center (CRC) TRR333 Brown and Beige Fat – Organ Crosstalk, Signaling and Energetics (BATenergy) is funded by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) and investigates metabolism/diabetes and focuses on brown adipose tissue.

TRR333 BATenergy Logo
TRR333 BATenergy Logo © Prof. Alexander Pfeifer

Recent publication in Nature!

Brown adipose tissue (BAT) dissipates energy and promotes cardio-metabolic health. In this publication, Nieman et al identifiy inosine as novel tissue-messenger in brown fat (BAT). They show that treatment of mice with inosine increased BAT-dependent energy expenditure and induced “browning” of white adipose tissue. This work was performed in close collaboration of projects P5, P10, P11, P15 and P16 of the CRC/TRR333 BATenergy.

Niemann, B., Haufs-Brusberg, S., Puetz, L. et al. Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine. Nature (2022).

Niemann et al.png
© Michelle Y. Jaeckstein and Jörg Heeren, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany

Participating universities and research institutions

The University of Bonn, the Universität Hamburg, the Technical University of Munich and the Helmholtz Center Munich are leading research organizations in the field of brown and beige adipose tissue in Germany. The CRC/TRR333 constitutes a unique possibility to bring together leading scientists in the field of brown and beige adipose tissue and energy homeostasis and foster their interaction. All participating institutions offer state-of-the-art research infrastructure and an outstanding environment for excellent research.

Deutschlandkarte, Standorte, Universität Bonn, Universität Hamburg, Technische Universität München, Helmholtzzentrum München
Map of Germany with the three sites of the CRCTRR333 © Bosse und Meinhard GbR, Reinhard Bosse. Michael Meinhard



TRR333 BATenergy Office Bonn

Lena Graziola

Universitätsklinikum Bonn

Institut für Pharmakologie & Toxikologie

Venusberg-Campus 1 53127 Bonn

+49 228 287-51300

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