Project P04
ExBat: Effect of acute and chronic exercise on human thermogenic adipose tissue & elucidation of mechanisms
© Wackerhage/Soriano
Exercise has many beneficial effects including a regulation of adaptive thermogenesis. Centered around the finding that exercise-conditioned sera from athletes enhance human adipocyte UCP1 expression, we will investigate the effect of different exercise modes and of exercise training on adaptive thermogenesis in humans. Mechanistically, this project will specifically investigate metabolites that regulate “browning” via phosphoproteomics and whether miRNAs in exosomes, termed exomiRs, mediate crosstalk in-between muscle and adipocytes especially during exercise.
Project Leaders
Prof. Dr. Henning Wackerhage
Fakultät für Sport- und Gesundheitswissenschaften
Conollystraße 32
80809 München
© Henning Wackerhage
Dr. Ana Soriano Arroquia
Institut für Pharmakologie und Toxikologie, Biomedizinisches Zentrum
Venusberg-Campus 1
53127 Bonn
© Ana Soriano