Project P06

Interactions of endothelium and adipocytes during thermogenic adaptation

P06.JPG
© AP

Brown adipose tissue (BAT) is highly vascularized. Changes in BAT functional states also stimulate the adaptation of the BAT vascular network. This suggests that there is a crosstalk between adipocytes and endothelial cells (ECs). So far, this is only poorly understood and the existing studies focus on angiogenesis in BAT, while this project specifically aims to identify auto/paracrine factors that regulate the interplay of ECs and how ECs adapt to the energetic needs of BAT.


Project Leaders

Avatar Pfeifer

Prof. Dr. med. Alexander Pfeifer

Universitätsklinikum Bonn

Institut für Pharmakologie & Toxikologie

Venusberg-Campus 1 53127 Bonn

+49 228 287-51300

Avatar Wilhelm-Jüngling

Prof. Dr. Kerstin Wilhelm-Jüngling

Universitätsklinikum Bonn

AG Endothelial Signaling & Metabolism

Venusberg Campus 1 53127 Bonn

+49 228 287-51368

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